Last January 2008, the leaves have been previously identified by a botanist at University Putra Malaysia (UPM) Serdang Selangor, and a voucher specimen (SK 964/04) has been preserved at the Herbarium of the laboratory of Natural product, Institute of Bioscience, UPM, Selangor, Malaysia. The fruits are edible and in some cases sold in markets, as they can be eaten raw or processed as jam; leaves can be used for making tea. Context: Different parts of Muntingia calabura L. (Elaeocarpaceae), or “kerukup siam” in Malay, have been reported to possess medicinal value, supported by a number of scientific studies.. Muntingia calabura L is a flowering plant native to southern mexico, central america, Caribbean, western to south America. This study aimed to analyse the antioxidant activity, total phenols, and flavonoids of kersen leaves (Muntingia calabura L.) extract (KLE) and determine the hepatoprotective activity of KLE in soft drink induced mice. The bark gives ropes and fiber for bark skirts. (6)(7) Muntingia calabura leaves extract exhibited significant pharmacological effects such as The leaves possess antinociceptive, anti-inflammatory and antipyretic activities [7]. Muntingia calabura is one of the many species from the family Muntingiaceae used in folk medicine throughout the world. The timbers are lightweight, durable and used in carpentry. They subjected the test extract for toxicity studies, and the reports revealed that no symptoms of toxicity observed up to a dosage of 2000 mg/kg body weight. In this study, the leaves were prepared as MEMCL and subjected to ethanol- and indomethacin-induced gastric ulcers wherein in the former assay the doses of 25, 50, 100, 250, and 500 mg/ kg were used while in the later assay, the doses of 100, 250, ad 500 mg/kg were used. The in vitro antiproliferative and antioxidant activities of the aqueous, chloroform and methanol extracts of Muntingia calabura leaves were determined in the present study. The purpose of this study was to determine the effectiveness of boiled cherry leaves (muntingia calabura L) and Figs leaves (Ficus Carica) to reduce SGOT SGPT levels. The leaf infusion of M. calabura at a concentration of 6% significantly inhibited EHI and AWM, higher than the negative control (P<0,05). View This Abstract Online; Methanolic Extract of Muntingia Calabura L. Mitigates 1,2-Dimethyl Hydrazine Induced Colon Carcinogenesis in Wistar Rats. The stem of Muntingia calabura was studied in the present study for its phytochemical analysis both qualitatively and … M. calabura is planted as a source of timber and fuel. Other than the Kerson fruit itself, it is also worth mentioning the … The study was designed to assess the acute toxicity and anti-inflammatory potential of methanolic extract of Muntingia calabura L. (MEMC) in in vivo models. The leaves are alternate, distichous, oblong or lanceolate, 4–15 cm long and 1–6 cm wide, with toothed margin and covered in short hairs. Our recent work encompasses the phytochemical profile and antioxidant activity to authenticate the medicinal properties of … The leaves and fruits were studied for its phytochemical analysis both qualitatively and quantitatively and also for its behavior with aqueous extract powders, fluorescence, nutrients. Bawa K, 1973. Abstract. Jisha N; Vysakh A; Vijeesh V; Anand PS; Latha MS. Fruit from Muntingia is also harvested for export overseas. Muntingia calabura, commonly known as Jamaican cherry, is a plant species belonging to the family Muntingiaceae with variety of traditional uses. The fruits of Muntingia calabura have antioxidant property [8]. Following on these folklore claims, the works on phytochemicals constituents, traditional uses, pharmacological benefits and their mechanisms are presented in a number of studies as well as the in vitro and in vivo investigations. Abstract. Inflammation is one of the warning signs of conditions like arthritis, certain … While, it was not significantly different from albendazole 2 mg/ml on EHI test. Objective: This study aimed to determine the cytotoxic activity of the methanolic extract of Muntingia calabura leaves against A549 Human lung adenocarcinoma cell line. Jamaica cherry scientifically known as Muntingia calabura is a fast-growing small evergreen belong to genus Muntingia L. (muntingia) of the Elaeocarpaceae (Elaeocarpus family). Anti-inflammatory Activity of Muntingia calabura Fruits Kathirvel Preethi,* Paramasivam Premasudha, Kittusamy Keerthana Department of Microbial Biotechnology, Bharathiar University, Coimbatore – 641 046 A B S t r A c t Muntingia calabura, the sole species in the genus Muntingia, is a flowering plant, that belongs to Elaeocarpaceae family. The timber of Jamaican cherry is reddish-brown, compact, durable, light weight and used in carpentry, firewood. Kerson Fruit for a Healthy Heart. Muntingia calabura L. (family Elaeocarpaceae) has been traditionally used to relieve various pain-related ailments. (5) Previous studies suggested Muntingia calabura as a great source of flavonoids which act as potent antioxidant agents, with the highest content of flavonoids lay within its leaves. The objects in this study were 30 male Wistar strain rats aged 2-3 months with a weight of 180-200 … Abstract. There were no abnormal signs, behavioural changes, body weight changes, or. Its soft wood used for rural construction, while the bark is fibrous and used for making ropes. Safety evaluation of orally-administered methanol extract of Muntingia calaburaLinn. Another study on the antiulcer potential of M. calabura leaves was studied. Muntingia calabura L. leaves were therapeutically used for ulcer, fever, headache etc. leaves: A sub-chronic toxicity study in Sprague Dawley rats Nur Liana Md Nasir1, Noorsyaza Eddrina Kamsani1, Norhafizah Mohtarrudin2, Siti Farah Md Tohid1and Zainul Amiruddin Zakaria1,3,* The present study investigates the qualitative and quantitative analysis of the major bioactive constituents of plant Muntingia calabura in some solvents … ABSTRACT The present investigation, describes the phytochemical analysis, in vitro antioxidant and antidiabetic property of Muntingia calabura leaves extracts along with estimate the inorganic components of the leaves. Journal of King Saud University-Science, 25(1), 83-89. Therefore, this review paper is presented to help guide researchers to plan their future studies related to this plant in the hope of isolating potential leads for future drug development. (11) Antioxidants are substances that can inhibit Reduces Inflammation. Based on previous research, M. calabura leaves was known to contain flavonoid compounds, tannins, triterpenoids, saponins, and polyphenols that showed antioxidant activity. The result showed that M. calabura leaves contain secondary metabolites, one of which was condensed tannins detected in this study. The results conclude that the leaf infusion of M. calabura is … such as Indonesia. Soft drinks induction causes liver injuries which increases the serum glutamic oxaloacetic transaminase (SGOT) and serum glutamic pyruvic transaminase (SGPT) levels. Nutr Cancer. Glycation and production of free radicals become important mechanisms underlying skin aging. The plant is native to southern Mexico, Central America, tropical South America, the Greater Antilles, St. Vincent and Trinidad. Citation: Ibrahim IAA, Abdulla MA, Abdelwahab SI, Al-Bayaty F, Majid NA (2012) Leaves Extract of Muntingia Calabura Protects Against Gastric Ulcer Induced by Ethanol in Sprague-Dawley Rats. Following the recent establishment of antinociceptive activity of M. calabura leaf, the present study was performed Keywords Elaeocarpaceae, ethnomedicinal uses, The inorganic components present in the leaves were estimated by Narendhirakannan method. Recent studies: There are also recent studies done about Muntingia Calabura Linn. ETHNOPHARMACOLOGICAL RELEVANCE: In traditional medicine, the leaves, flowers, barks and roots of Muntingia calabura L. (Muntingiaceae) have been employed as a treatment for various ailments including dyspepsia and to relieve pain caused by gastritis and peptic ulcer disease. ''Muntingia calabura'' is a shrub or tree up to 12 m tall with spreading branches. Anti-inflammatory Activity: N. Jisha et al., (2019) published a research study on the anti-inflammatory potential of Muntingia calabura leaves methanol extract on female Wistar rats. Background: Muntingia calabura (Elaecoparceae) is a medicinal plant traditionally used, particularly, by the Peruvian people to alleviate headache and cold, pain associated with gastric ulcers or to reduce the prostate gland swelling. The present study aimed to determine the antinociceptive activity of methanol extract of M. calabura leaves (MEMC) and to elucidate the possible mechanism of antinociception involved. 2020; :1-13 (ISSN: 1532-7914). Various parts of M. calabura such as leaves, barks, flowers, and roots have Conclusion: Muntingia calabura possesses remarkable medicinal value, which warrants further and in-depth studies. 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